What is Skelaxin

Skelaxin relaxes muscles and relieves pain and discomfort associated with strains, sprains, spasms or other muscle injuries.

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General Information for Skelaxin

SKELAXIN DRUG INFO

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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

SKELETAL MUSCLE RELAXANTS - ORAL

COMMON BRAND NAME(S): Parafon Forte DSC, Robaxin, Skelaxin

USES: This medication relaxes muscles and relieves pain and discomfort associated with strains, sprains, spasms or other muscle injuries.

HOW TO USE: May be taken with food or immediately after meals to prevent stomach upset. Do not increase your dose, take it more frequently or take it for a longer period of time than prescribed by your doctor.

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Safety Information for Skelaxin

SIDE EFFECTS: May cause stomach upset, heartburn, constipation, headache, dizziness or drowsiness the first few days as your body adjusts to the medication. If these symptoms persist or become severe, notify your doctor. Inform your doctor if you develop: persistent stomach pain, skin rash, itching, rapid heart rate, yellowing of eyes or skin. May discolor urine. This will disappear when the medication is stopped. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: seizures, kidney or liver disease, any drug allergies. Alcoholic beverages may increase the dizziness/drowsiness effects of this drug. Limit alcohol intake. Use caution engaging in activities requiring alertness such as driving or operating machinery. When arising quickly from a sitting or lying position, this drug may cause dizziness/lightheadedness. Change positions slowly. This medication should be used during pregnancy only when clearly needed. Discuss the risks and benefits with your doctor. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of any over-the-counter or prescription medication you take including any medication such as: sedatives, tranquilizers, narcotics (pain medication), sleeping pills, medication for seizures, depression, allergies, hay fever, colds. Do not start taking any of the drugs mentioned above without consulting your doctor. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include severe drowsiness or unconsciousness.

NOTES: This medication provides temporary relief and must be used in addition to rest, physical therapy and other measures as directed by your doctor. Do not allow anyone else to take this medication.

MISSED DOSE: If you miss a dose, take as soon as remembered within 1 hour. Otherwise skip that dose and resume usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom.

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NEWS

The Elan Corporation said today that it had settled its legal battle with King Pharmaceuticals of Bristol, Tenn., over the sale of rights to two of Elan's drugs in the United States to King.

King had tried to back out of the original deal, which included the transfer to King of a 375-member American sales force for the two drugs -- Sonata, a sleeping pill, and Skelaxin, a muscle relaxant. Under the settlement, King will go through with the purchase, but on more favorable terms than before: it will pay $750 million instead of $890 million. King agreed to pay Elan some continuing royalties on the drugs and a bonus if Skelaxin, a 40-year-old drug, retains patent protection through next January.

The settlement comes five days after hearings in Elan's lawsuit against King to force the completion of the sale were to have begun in New York State Supreme Court. The hearings were unexpectedly postponed last week.

Elan badly needs the cash it will reap from the deal to pay down debt. Investors reacted to the settlement by bidding Elan's stock up 8.6 percent to 4.06 euros ($4.75) a share in Dublin. A share of King fell 25 cents, to $12.99 in New York.

''The foundation was there, certainly, for some dialogue, for a win-win situation,'' G. Kelly Martin, Elan's chief executive, said in a telephone interview today from his home in California. ''Neither King nor ourselves really wanted to spend three months in litigation.''

In a statement, Kyle P. Macione, president of King, called the deal ''a transformational event for our company'' that will allow it ''to compete even more effectively in the primary care marketplace.''

King balked at the original agreement in March after the Federal Trade Commission began an inquiry into how Elan had marketed Skelaxin. But analysts said that King might have been using the inquiry, which was dropped by the commission on May 8, as a pretext to escape a deal that it had come to believe was overpriced. The two drugs had combined sales of $238 million in the United States last year.

Elan needs to raise $1.5 billion by the end of 2003 to pay back part of its $2.6 billion in debts and other commitments. The sale puts Elan over its goal, the company said today.

''It's potentially a billion-plus transaction for Elan over the life of the contract,'' when the royalties and other payments are included, Mr. Martin said. Even so, he said, Elan expects to sell off more assets in the next few weeks. ''We want to continue to streamline the business,'' he said.

Analysts expressed relief that the settlement removed some uncertainty from Elan, which was the most valuable public company in Ireland in 2001, but has since lost more than 90 percent of its market capitalization and now ranks ninth. ''The market is looking at this from a liquidity point of view,'' said Peter Frawley, an equity analyst with Merrion Stockbrokers in Dublin.

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